Nalfurafine Suppresses Pruritogen- and Touch-evoked Scratching Behavior in Models of Acute and Chronic Itch in Mice
Authors:
- T AkiyamaTAT Akiyama
- S SteppanSSS Steppan
- E CarstensECE Carstens
Open Access
- 1 February 2015
- journal article
- Published by Medical Journals Sweden AB in Acta Dermato-Venereologica
- Vol. 95 (2) , 147-150
Abstract
The kappa-opioid agonist, nalfurafine, has been approved in Japan for treatment of itch in patients ...Keywords
This publication has 23 references indexed in Scilit:
- A feed-forward spinal cord glycinergic neural circuit gates mechanical allodyniaJournal of Clinical Investigation, 2013
- Activity-dependent silencing reveals functionally distinct itch-generating sensory neuronsNature Neuroscience, 2013
- Cross-sensitization of histamine-independent itch in mouse primary sensory neuronsNeuroscience, 2012
- Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced PruritusCell, 2009
- Glycine Inhibitory Dysfunction Induces a Selectively Dynamic, Morphine-Resistant, and Neurokinin 1 Receptor- Independent Mechanical AllodyniaJournal of Neuroscience, 2009
- Uraemic PruritusDrugs, 2009
- Spontaneous scratching behavior in MRL/lpr mice, a possible model for pruritus in autoimmune diseases, and antipruritic activity of a novel κ-opioid receptor agonist nalfurafine hydrochlorideEuropean Journal of Pharmacology, 2005
- Kappa opioid agonists suppress chloroquine-induced scratching in miceEuropean Journal of Pharmacology, 2004
- Involvement of central μ-opioid system in the scratching behavior in mice, and the suppression of it by the activation of κ-opioid systemEuropean Journal of Pharmacology, 2003
- Opiate and H1 antagonist effects on histamine induced pruritus and alloknesisPain, 1997