De novo formation of a distinct coronary vascular population in neonatal heart

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Abstract
The heart needs blood vessels, too: For the newborn heart to grow quickly, the heart's own blood vessels must grow as well. Researchers have assumed that preexisting fetal coronary vessels expand to cause this postnatal coronary vascular growth. Instead, Tian et al. now show that, for the most part, brandnew blood vessels form within the neonatal heart (see the Perspective by Burns and Burns). This ability to produce new coronary blood vessels after birth may one day help researchers work out how to promote cardiovascular regeneration after injury or disease. Science , this issue p. 90 ; see also p. 28

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