Phosphorous-containing, amphiphilic ABB′ copolymers as siRNA nanocarriers with enhanced stability, reduced in vitro cytotoxicity, and efficient knockdown ability for the treatment of ocular diseases

Authors:
Open Access
Publisher website
Google Scholar
Abstract
Using phosphorus-containing, cationic polymers synthesized by REM-GTP, novel siRNA delivery agents were developed that demonstrate excellent siRNA encapsulation and efficient endosomal escape and gene silencing, while showing low cytotoxicity.
Funding Information
  • Technische Universität München
  • Studienstiftung des Deutschen Volkes
  • Bundesministerium für Forschung, Technologie und Raumfahrt
  • Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg

This publication has 54 references indexed in Scilit: