Comparative Homology Modeling and Ligand Docking Study of Human Catechol-O-Methyltransferase for Antiparkinson Drug Design
Authors:
- Jeeyoung LeeJLJeeyoung Lee
- Yangmee KimYKYangmee Kim
- 20 November 2005
- journal article
- Published by Korean Chemical Society in Bulletin of the Korean Chemical Society
- Vol. 26 (11) , 1695-1700
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase foldCurrent Opinion in Structural Biology, 2002
- Kinetics and Crystal Structure of Catechol-O-Methyltransferase Complex with Co-Substrate and a Novel Inhibitor with Potential Therapeutic ApplicationMolecular Pharmacology, 2002
- Catechol-O-Methyltransferase (COMT)-Mediated Methylation Metabolism of Endogenous Bioactive Catechols and Modulation by Endobiotics and Xenobiotics: Importance in Pathophysiology and PathogenesisCurrent Drug Metabolism, 2002
- Catecholamine metabolism in the brain by membrane-bound and soluble catechol-o-methyltransferase (COMT) estimated by enzyme kinetic valuesMedical Hypotheses, 2001
- Catechol-O-Methyltransferase Decreases Levodopa Toxicity In VitroClinical Neuropharmacology, 2001
- Comparative Protein Structure Modeling of Genes and GenomesAnnual Review of Biophysics, 2000
- Clinical Pharmacology, Therapeutic Use and Potential of COMT Inhibitors in Parkinson???s DiseaseDrugs, 2000
- Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy functionJournal of Computational Chemistry, 1998
- Purification methods of mammalian catechol-O-methyltransferasesJournal of Chromatography B: Biomedical Sciences and Applications, 1996
- PROCHECK: a program to check the stereochemical quality of protein structuresJournal of Applied Crystallography, 1993