Organocatalytic Cascade Reactions for the Synthesis and Diversification of Privileged Structures

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Abstract
Herein, we present the development of new organocatalytic cascade reactions for the synthesis and diversification of privileged structures, using trienamine activation as a key step. An important feature of this process is that once it is completed, it is possible to generate new reactive species within the same molecule. In this sense, a series of consecutive reactions can be carried out, incorporating dienophiles with a nucleophilic addition functionality. As a result, complex and diverse compounds can be accessed through simple starting materials.
Funding Information
  • Ciencia Básica y de Frontera 2023–2024 (BF2023-2024-266, 150/2024, 090/2024)
  • DAIP-UG (BF2023-2024-266, 150/2024, 090/2024)