A Plasmodium falciparum lysophospholipase regulates host fatty acid flux via parasite lipid storage to enable controlled asexual schizogony
Authors:
- Pradeep Kumar SheokandPSPradeep Kumar Sheokand
- Yoshiki Yamaryo-BottéYYYoshiki Yamaryo-Botté
- Monika NarwalMNMonika Narwal
- Christophe-Sébastien ArnoldCAChristophe-Sébastien Arnold
- Vandana ThakurVTVandana Thakur
- Muzahidul IslamMIMuzahidul Islam
- Mudassir M. BandayMBMudassir M. Banday
- Mohd AsadMAMohd Asad
- Cyrille Y. BottéCBCyrille Y. Botté
- Asif MohmmedAMAsif Mohmmed
Open Access
- 3 April 2023
- journal article
- research article
- Published by Elsevier in Cell Reports
- Vol. 42 (4)
Abstract
No abstract availableFunding Information
- University Grants Commission
- Agence Nationale de la Recherche
- International Centre for Genetic Engineering and Biotechnology
- Université Grenoble Alpes
- Government of India Department of Biotechnology
- CNRS
- Région Auvergne-Rhône-Alpes
- Région Auvergne-Rhône-Alpes (6003-1)
- Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation
- CEFIPRA
- Fondation pour la Recherche Médicale (FRM EQU202103012700)
This publication has 40 references indexed in Scilit:
- Inducible Knockdown of Plasmodium Gene Expression Using the glmS RibozymePLOS ONE, 2013
- The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected DiseasesPLOS ONE, 2013
- Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasitesProceedings of the National Academy of Sciences, 2013
- The Kennedy phospholipid biosynthesis pathways are refractory to genetic disruption in Plasmodium berghei and therefore appear essential in blood stagesMolecular and Biochemical Parasitology, 2010
- Targeting the lipid metabolic pathways for the treatment of malariaDrug Development Research, 2009
- Disruption of the Plasmodium falciparum PfPMT Gene Results in a Complete Loss of Phosphatidylcholine Biosynthesis via the Serine-Decarboxylase-Phosphoethanolamine-Methyltransferase Pathway and Severe Growth and Survival DefectsJournal of Biological Chemistry, 2008
- An FKBP destabilization domain modulates protein levels in Plasmodium falciparumNature Methods, 2007
- Inhibition of Plasmodium falciparum Choline Kinase by Hexadecyltrimethylammonium Bromide: a Possible Antimalarial MechanismAntimicrobial Agents and Chemotherapy, 2007
- Neutral-Lipid Analysis Reveals Elevation of Acylglycerols and Lack of Cholesterol Esters in Plasmodium falciparum -Infected ErythrocytesEukaryotic Cell, 2003
- A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening AssaysSLAS Discovery, 1999