Familial occurrence of congenital laryngeal clefts

Authors:
  • PPP. D. Phelan
    P. D. Phelan
  • JSJ. G. Stocks
    J. G. Stocks
  • HWH. E. Williams
    H. E. Williams
  • DDD. M. Danks
    D. M. Danks

Abstract
Two sibships of double first cousins in which 6 children had congenital laryngeal anomalies are reported. 3 of the children had proven congenital posterior laryngeal clefts, 1 had subglottic stenosis with a deformed cricoid cartilage, and it is likely that the other 2 also had posterior laryngeal clefts. It is suggested that the anomaly is inherited as an autosomal dominant.

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