Design, synthesis, anticancer evaluation and molecular docking study of novel 2,4-dichlorophenoxymethyl-based derivatives linked to nitrogenous heterocyclic ring systems as potential CDK-2 inhibitors

This publication has 48 references indexed in Scilit:

• Synthesis of novel quinoline-2-one based chalcones of potential anti-tumor activity
  European Journal of Medicinal Chemistry, 2012
• Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways
  Proceedings of the National Academy of Sciences, 2012
• Utility of Phthalimidoacyl Isothiocyanate in Synthesis of Quinazolines, Benzoxazoles, Benzimidazoles, 1,2,4-Triazoles, and Oxatriazepines
  Phosphorus, Sulfur, and Silicon and the Related Elements, 2012
• Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating epidermal growth factor receptor mutation: Review of the evidence
  Lung Cancer, 2011
• Design, synthesis, and biological evaluation of novel pyrimidine derivatives as CDK2 inhibitors
  European Journal of Medicinal Chemistry, 2010
• Synthesis, antimicrobial and cytotoxic activities of 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles
  European Journal of Medicinal Chemistry, 2009
• Cell cycle, CDKs and cancer: a changing paradigm
  Nature Reviews Cancer, 2009
• Bcl-2 family proteins and cancer
  Oncogene, 2008
• CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases
  Oncogene, 2008
• AZ703, an Imidazo[1,2-a]Pyridine Inhibitor of Cyclin-Dependent Kinases 1 and 2, Induces E2F-1-Dependent Apoptosis Enhanced by Depletion of Cyclin-Dependent Kinase 9
  Cancer Research, 2006