NUCLEAR PRECIPITATES IN PYROANTIMONATE-OSMIUM TETROXIDE-FIXED TISSUES

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Abstract
Recent biochemical studies indicate a significant role for sodium ions in nuclear metabolism. Protein and nucleic acid syntheses in the nucleus depend upon sodium, apparently through a stimulating effect of this cation on the transport of amino acid, purine, and pyrimidine into the nucleus (1). The nuclei of avian erythrocytes and calf thymocytes appear to contain higher sodium concentrations than the cytoplasm (5), and the nuclei of frog oocytes actively incorporate and concentrate sodium as shown by radioautography with Na 2a+ (1).

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