Synthesis of tetrachloroisophthalo‐[14C]‐nitrile
- 1 March 1984
- journal article
- research article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 21 (3) , 285-292
Abstract
A low cost, high yield synthesis of tetrachloroisophthalo‐[14C]‐nitrile (TCIN) is described. Direct replacement of iodine in 3‐iodobenzonitrile using 14C‐labeled cuprous cyanide, and vapour phase chlorination yields [14C]‐TCIN, with maximum utilisation of the radiolabel. Alternative and unsuccessful routes are also briefly described.Keywords
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