Performance-Based Measures of Everyday Function in Mild Cognitive Impairment

Authors:
  • JKJeremy Koppel
    Jeremy Koppel
  • LKLynda Keehlisen
    Lynda Keehlisen
  • ECErica Christen
    Erica Christen
  • UDUte Dreses-Werringloer
    Ute Dreses-Werringloer
  • CCConcepcion Conejero-Goldberg
    Concepcion Conejero-Goldberg
  • MGMarc L. Gordon
    Marc L. Gordon
  • PDPeter Davies
    Peter Davies
Publisher website
Google Scholar
Abstract
ObjectiveThe view that everyday function is preserved in mild cognitive impairment may be problematic. The objectives of this study were to determine the magnitude of impairment in everyday function in patients with mild cognitive impairment and Alzheimer's disease using a novel sensitive performance-based measure (the UCSD Performance-Based Skills Assessment; UPSA), contrast it with use of an informant-based measure (the Alzheimer's Disease Cooperative Study–Activities of Daily Living Inventory; ADCS-ADL), and model the relationship between cognitive measures and the performance-based measure. MethodFifty cognitively normal elders, 26 patients who met criteria for amnestic mild cognitive impairment, and 22 patients who suffered from mild to moderate Alzheimer's disease were assessed on the UPSA, the ADCS-ADL, and a battery of neurocognitive tests. ResultsPatients with mild cognitive impairment had significant impairments on the UPSA but not on the ADCS-ADL. The magnitude of the effect size between the co...

This publication has 42 references indexed in Scilit: