Ocular Toxicity of Hydroxychloroquine
Authors:
- 1 January 2008
- journal article
- review article
- Published by Taylor & Francis in Seminars in Ophthalmology
- Vol. 23 (3) , 201-209
Abstract
This review summarizes the current literature regarding the ocular complications of hydroxychloroquine. Hydroxychloroquine has been used since the 1950s for the treatment of various rheumatic and dermatologic diseases. Hydroxychloroquine can cause ocular toxicity, with the most serious being an irreversible retinopathy. At the present time, no "gold standard" exists for identification of the ocular toxicity prior to its development. This has led to controversy regarding the recommendations for ophthalmologic examinations for screening patients on hydroxychloroquine.Keywords
This publication has 40 references indexed in Scilit:
- New concepts in antimalarial use and mode of action in dermatologyDermatologic Therapy, 2007
- High-Speed Ultra–High-Resolution Optical Coherence Tomography Findings in Hydroxychloroquine RetinopathyArchives of Ophthalmology (1950), 2007
- Multifocal Electroretinographic Changes in Patients Receiving Hydroxychloroquine TherapyAmerican Journal of Ophthalmology, 2005
- Recommendations on screening for chloroquine and hydroxychloroquine retinopathyOphthalmology, 2002
- Ocular toxicity and antenatal exposure to chloroquine or hydroxychloroquine for rheumatic diseasesThe Lancet, 2001
- Ocular toxicity and hydroxychloroquine: guidelines for screeningBritish Journal of Dermatology, 1999
- Incidence of hydroxychloroquine retinopathy in 1,207 patients in a large multicenter outpatient practiceArthritis & Rheumatism, 1997
- The ocular safety of hydroxychloroquineSeminars in Arthritis and Rheumatism, 1993
- Ocular Changes Induced by Long-Term Hydroxychloroquine (Plaquenil) TherapyAmerican Journal of Ophthalmology, 1967
- RETINOPATHY FOLLOWING CHLOROQUINE THERAPYThe Lancet, 1959