Scientific substantiation of a herbal blend based on puncturevine, alfalfa, and field penny cress with addition of microelements to support men’s health

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Abstract
The study presents data justifying the composition of a combined herbal blend to improve men’s health, based on three types of medicinal plant materials: puncturevine (Tribulus terrestris), alfalfa (Medicago sativa), and field penny‑cress (Thlaspi arvense), as well as trace elements. The aim of the study is to summarize available literature on the chemical composition, pharmacological properties, and primary uses of the components of the herbal blend. Materials and methods. A review of publications over the past 40 years was conducted in peer‑reviewed databases to identify trends in the use of the studied plants for the prevention and treatment of conditions related to men’s health. Results. Tribulus terrestris (puncturevine) exhibits adaptogenic, anabolic, and antioxidant activity and improves sperm motility and viability. Medicago sativa (alfalfa) contains saponins, flavonoids, phytoestrogens, and a complex of vitamins; it stimulates spermatogenesis, increases testosterone levels, and has anti‑inflammatory and hypolipidemic effects. Thlaspi arvense (field penny‑cress) enhances fertility, improves semen quality, and demonstrates membrane‑protective and antioxidant effects. The role of trace elements (iron, copper, manganese, zinc) in supporting male reproductive function is justified from a physiological and biochemical perspective. An optimized composition of the herbal blend is proposed, including daily doses of plant components and trace elements. Conclusion. The developed herbal blend has a comprehensive positive effect on androgenic status and spermatogenesis, exhibits antioxidant and hypolipidemic properties, and can be used in andrological practice as well as a dietary supplement for athletes and individuals leading an active lifestyle.

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