Evaluation of MR thermometry with proton resonance frequency method at 7T
Author:
- 1 April 2017
- journal article
- research article
- Published by AME Publishing Company in Quantitative Imaging in Medicine and Surgery
- Vol. 7 (2) , 259-266
Abstract
Quantitative and non-invasive temperature mapping using magnetic resonance imaging (MRI) provides a unique way to measure temperature evolution inside biological tissues. The method is widely used in thermal ablation procedures with magnetic fields at or below 3T. In this paper, the sensitivity of the MRI thermometry at 7T was studied using a proton resonance frequency (PRF)-based technique. We first used an agarose gel phantom with MR-compatible thermometry to calibrate the temperature coefficient, and then this temperature coefficient was employed to measure the internal temperature in both ex vivo (beef muscle) and in vivo (rat) experiments using focused ultrasound heating. The temperature coefficient calibrated by the phantom was 0.0095 ppm/°C, and both the ex vivo and in vivo experiments exhibited clear temperature evolution. This quantitative study confirmed the sensitivity (<1 °C) of MR temperature mapping at 7T.Keywords
This publication has 29 references indexed in Scilit:
- Magnetic Resonance Thermometry at 7T for Real-Time Monitoring and Correction of Ultrasound Induced Mild HyperthermiaPLOS ONE, 2012
- MR-guided transcranial brain HIFU in small animal modelsPhysics in Medicine & Biology, 2009
- Long-term survival following a single treatment of kidney tumors with multiwalled carbon nanotubes and near-infrared radiationProceedings of the National Academy of Sciences, 2009
- Validation of fast MR thermometry at 1.5 T with gradient‐echo echo planar imaging sequences: phantom and clinical feasibility studiesNMR in Biomedicine, 2008
- MR thermometryJournal of Magnetic Resonance Imaging, 2008
- Optimization of self-reference thermometry using complex field estimationMagnetic Resonance in Medicine, 2006
- Uterine Leiomyomas: MR Imaging–based Thermometry and Thermal Dosimetry during Focused Ultrasound Thermal AblationRadiology, 2006
- Real‐time MR temperature mapping of rabbit liver in vivo during thermal ablationMagnetic Resonance in Medicine, 2003
- Temperature quantification using the proton frequency shift technique: In vitro and in vivo validation in an open 0.5 tesla interventional MR scanner during RF ablationJournal of Magnetic Resonance Imaging, 2001
- Noninvasive MRI Thermometry with the Proton Resonance Frequency (PRF) Method: In Vivo Results in Human MuscleMagnetic Resonance in Medicine, 1995