Synthesis of 2α-propoxy-1α,25-dihydroxyvitamin D3 and comparison of its metabolism by human CYP24A1 and rat CYP24A1
- 1 July 2009
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 17 (13) , 4296-4301
Abstract
No abstract availableKeywords
Funding Information
- Japan Society for the Promotion of Science
- Ministry of Education, Culture, Sports, Science and Technology
This publication has 32 references indexed in Scilit:
- Synthesis and Anti-inflammatory Properties of 1α,25-Dihydroxy-16-ene-20-cyclopropyl-24-oxo-vitamin D3, a Hypocalcemic, Stable Metabolite of 1α,25-Dihydroxy-16-ene-20-cyclopropyl-vitamin D3Journal of Medicinal Chemistry, 2009
- Vitamin D analogs: Therapeutic applications and mechanisms for selectivityMolecular Aspects of Medicine, 2008
- Evolution of our understanding of vitamin DNutrition Reviews, 2008
- Structural Refinement of seco-Steroidal Skeleton and the Biological Activity through Nuclear ReceptorsYAKUGAKU ZASSHI, 2008
- Synthesis, Biological Evaluation, and Conformational Analysis of A-Ring Diastereomers of 2-Methyl-1,25-dihydroxyvitamin D3 and Their 20-Epimers: Unique Activity Profiles Depending on the Stereochemistry of the A-Ring and at C-20Journal of Medicinal Chemistry, 2000
- Syntheses and biological evaluation of novel 2α-substituted 1α,25-dihydroxyvitamin D3 analoguesBioorganic & Medicinal Chemistry Letters, 2000
- Convergence of Transforming Growth Factor-β and Vitamin D Signaling Pathways on SMAD Transcriptional CoactivatorsScience, 1999
- A novel and practical route to A-ring enyne synthon for 1α,25-dihydroxyvitamin D3 analogs: Synthesis of A-ring diastereomers of 1α,25-dihydroxyvitamin D3 and 2-methyl-1,25-dihydroxyvitamin D3Bioorganic & Medicinal Chemistry Letters, 1998
- The vitamin D endocrine system and its therapeutic potential1996
- The Steroid and Thyroid Hormone Receptor SuperfamilyScience, 1988