Solvent quality and solvent polarity in polypeptides
Open Access
- 4 January 2023
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Physical Chemistry Chemical Physics
- Vol. 25 (6) , 4839-4853
Abstract
Synthetic polymers assume a compact/extended conformation in a poor/good solvent. Proteins, formed by both hydrophobic and polar moieties fold in water but not in apolar solvents. This difference can be rationalized and quantified by calculating the solvation free energy.Keywords
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Funding Information
- Ministero dell’Istruzione, dell’Università e della Ricerca (2017Z55KCW)
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