Synthesis of some 2-Pyridones by Application of L-L Phase Transfer Catalysis Method
- 14 July 2020
- journal article
- research article
- Published by Trans Tech Publications, Ltd. in Materials Science Forum
- Vol. 1002, 448-456
Abstract
Phase transfer catalysis P.T.C is one of the most widely used techniques in the preparation of a wide range of compounds not only in organic chemistry but also a broadly useful in several other areas of chemistry. There have been extensive studies that have been used to synthesize many compounds that are biologically important with highly efficient and the percentage of the product and purity are high with perfect time. In this study, a number of chalcones were prepared and reacted with phenoxy acetamide, 4-methyl phenoxy acetamide and phenyl mercapto acetamide for the preparation of 2–pyridones compounds under phase transfer catalysis conditions. The reaction mechanism and the structure of the resulting compounds were determined using physical analysis methods IR and 1 H-NMR. 13 C-NMR was also measured for some compounds.Keywords
This publication has 25 references indexed in Scilit:
- Active Pharmaceutical Ingredients in Synthesis2018
- Thermal solvent-free synthesis of chromonyl chalcones, pyrazolines and their in vitro antibacterial, antifungal activitiesJournal of Enzyme Inhibition and Medicinal Chemistry, 2011
- The synthesis and Angiotensin Converting Enzyme (ACE) inhibitory activity of chalcones and their pyrazole derivativesBioorganic & Medicinal Chemistry Letters, 2010
- Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivativesEuropean Journal of Medicinal Chemistry, 2009
- In-vitroevaluation of selected chalcones for antioxidant activityJournal of Enzyme Inhibition and Medicinal Chemistry, 2008
- A review of anti-infective and anti-inflammatory chalconesEuropean Journal of Medicinal Chemistry, 2007
- Rapid microwave-assisted solution phase synthesis of substituted 2-pyridone librariesTetrahedron, 2004
- Liquid–Liquid Phase Transfer Catalysis: Basic Principles and Synthetic ApplicationsCatalysis Reviews, 2003
- Chalcones and flavonoids as anti-Tuberculosis agentsBioorganic & Medicinal Chemistry, 2002
- Conformational preferences of non-nucleoside HIV-1 reverse transcriptase inhibitorsTetrahedron, 2001