Efficacy of the PanCareFollowUp eHealth Lifestyle Intervention for Survivors of Childhood, Adolescent and Young Adult Cancer
Open Access
- 28 February 2025
- journal article
- Published by Wiley in Cancer Medicine
- Vol. 14 (5) , e70694
Abstract
Purpose: A healthy lifestyle may prevent or mitigate late effects in childhood, adolescent and young adult (CAYA) cancer survivors. To support survivors in adopting healthier behaviours, the PanCareFollowUp (PCFU) Lifestyle intervention was developed, encompassing 4 months of online lifestyle coaching aimed at achieving a personal lifestyle goal. The aims of this study were to (1) determine the efficacy of this intervention on lifestyle outcomes over time and (2) identify predictors for goal achievement.Patients and Methods: Fifty‐eight survivors were enrolled. Outcomes were assessed at baseline (T0), after 4 months of coaching (T1) and after 4 months of follow‐up (T2). The primary outcome included the percentage of survivors successful in achieving and sustaining their goal, whereas secondary outcomes included differences in body mass index (BMI), diet and physical activity. To evaluate the adjusted, longitudinal effects on secondary outcomes, linear mixed models were estimated. Predictors for goal achievement were identified through logistic regression analysis.Results: At T1 and T2, 68% and 76% of goals were achieved or sustained, respectively. Mean differences between T2 and T0 showed significant improvements in BMI (−0.5 kg/m2), diet (−0.6 points) and physical activity (+7.7 h/week). Estimation of multivariable models also showed positive effects. Participants with a lower BMI and fewer depressive feelings at baseline were more likely to achieve and/or sustain their goals at T2.Conclusion: Findings suggest that the PCFU Lifestyle intervention supports survivors in making lifestyle changes. Results can be used to inform a subsequent randomised intervention study and integrate lifestyle coaching into care.Trial Registration: International Clinical Trial Registry Platform (ICTRP) number: NL8932 (ICTRP Search Portal [who. int]). Registered on 29 September 2020Keywords
Funding Information
- European Commission (824982)
This publication has 31 references indexed in Scilit:
- The Coaching on Lifestyle (CooL) Intervention for Overweight and Obesity: A Longitudinal Study into Participants’ Lifestyle ChangesInternational Journal of Environmental Research and Public Health, 2018
- Mental health of long‐term survivors of childhood and young adult cancer: A systematic reviewInternational Journal of Cancer, 2018
- Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with ObesityCell Metabolism, 2016
- Validation of Self-Management Screening (SeMaS), a tool to facilitate personalised counselling and support of patients with chronic diseasesBMC Family Practice, 2015
- One-Year Results of theBeweegKuurLifestyle Intervention Implemented in Dutch Primary Healthcare SettingsBioMed Research International, 2015
- Physical Activity, Fitness, and Cardiometabolic Risk Factors in Adult Survivors of Childhood Cancer with a History of Hematopoietic Cell TransplantationTransplantation and Cellular Therapy, 2015
- Exercise and Risk of Major Cardiovascular Events in Adult Survivors of Childhood Hodgkin Lymphoma: A Report From the Childhood Cancer Survivor StudyJournal of Clinical Oncology, 2014
- Lifestyle and metabolic syndrome in adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort StudyCancer, 2014
- Predictors of inactive lifestyle among adult survivors of childhood cancerCancer, 2009
- The General Self-Efficacy Scale: Multicultural Validation StudiesThe Journal of Psychology, 2005