Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells
Authors:
Open Access
- 25 November 2016
- journal article
- research article
- Published by Impact Journals, LLC in Oncotarget
- Vol. 8 (12) , 18832-18847
Abstract
Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cellsKeywords
This publication has 68 references indexed in Scilit:
- RhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cellsCell Death & Disease, 2013
- Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent MannerCell, 2011
- Glutamine addiction: a new therapeutic target in cancerTrends in Biochemical Sciences, 2010
- Interplay between Cdh1 and JNK activity during the cell cycleNature Cell Biology, 2010
- Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant functionProceedings of the National Academy of Sciences, 2010
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancerOncogene, 2009
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolismNature, 2009
- Genomic stability and tumour suppression by the APC/C cofactor Cdh1Nature Cell Biology, 2008
- Tenets of PTEN Tumor SuppressionCell, 2008
- Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic modelProceedings of the National Academy of Sciences, 2006