Abstract
PURPOSE: Wavefront-guided laser refractive surgery induces postoperative optical aberrations that are not explained by the ablation profile. METHODS: A conceptual model is presented for a potential mechanism of surgically-induced corneal shape change that is dependent on structural modification, rather than ablation profile. RESULTS: Examples are provided from clinical and basic studies that are consistent with the proposed model. CONCLUSION: Corneal biomechanical response to ablative surgery may significantly affect outcomes, and should be taken into account when planning customized procedures. [J Refract Surg 2002;18:S589-S592]

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