Detection of Rocky Mountain spotted fever antibodies by a latex agglutination test
Authors:
- K E HechemyKHK E Hechemy
- R L AnackerRAR L Anacker
- R N PhilipRPR N Philip
- K T KleemanKKK T Kleeman
- J N MacCormackJMJ N MacCormack
- S J SasowskiSSS J Sasowski
- E E MichaelsonEME E Michaelson
- 1 August 1980
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 12 (2) , 144-150
Abstract
A latex test for immunodiagnosis of Rocky Mountain spotted fever, using erythrocyte-sensitizing substance from Rickettsia rickettsii adsorbed to latex particles, has been developed. The test was evaluated with a total of 123 single and 118 paired human sera submitted for Rocky Mount spotted fever testing. This test is simple, sensitive, and specific. Its efficiency, relative to the reference microimmunofluorescence test, was 95.1% for single sera and approached 100% for paired sera.Keywords
This publication has 9 references indexed in Scilit:
- Predictive Value of a Single Diagnostic Test: A Belated CorrectionNew England Journal of Medicine, 1979
- A COMPARISON OF SEROLOGIC METHODS FOR DIAGNOSIS OF ROCKY MOUNTAIN SPOTTED FEVERAmerican Journal of Epidemiology, 1977
- Antigen distribution in a latex suspension and its relationship to test sensitivityJournal of Clinical Microbiology, 1976
- Microimmunofluorescence test for the serological study of rocky mountain spotted fever and typhusJournal of Clinical Microbiology, 1976
- Indirect hemagglutination test for human antibody to typhus and spotted fever group rickettsiaeJournal of Clinical Microbiology, 1975
- Immunological Properties of Rickettsia rickettsii Purified by Zonal CentrifugationInfection and Immunity, 1975
- Latex Test for Quantitative Determination of Escherichia coli AntibodyApplied Microbiology, 1974
- Detection of Escherichia coli antigens by a latex agglutination test.1974
- A microagglutination technique for detection and measurement of rickettsial antibodies.1969