Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery
Open Access
- 31 December 2021
- journal article
- research article
- Published by Springer Nature in Scientific Reports
- Vol. 11 (1) , 1-13
Abstract
Latex, a milky substance found in a variety of plants which is a natural source of biologically active compounds. In this study, Latex was collected from rawCarica papayaand was characterized using UV–Vis, FTIR and GC–MS analyses. Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) were synthesized, coated withC. papayalatex (PL-Sp) and characterized using UV–Vis, FT-IR, SEM–EDX, XRD, VSM and Zeta potential analyses. SPIONs and latex coated SPIONs (PL-Sp) were used in batch adsorption study for effective removal of Methylene blue (MB) dye, where (PL-Sp) removed MB dye effectively. Further the PL-Sp was used to produce a nanoconjugate loaded with curcumin and it was characterized using UV–Vis spectrophotometer, FT-IR, SEM–EDX, XRD, VSM and Zeta potential. It showed a sustained drug release pattern and also found to have good antibacterial and anticancer activity.Keywords
This publication has 44 references indexed in Scilit:
- pH-responsive drug delivery of chitosan nanoparticles as Tamoxifen carriers for effective anti-tumor activity in breast cancer cellsColloids and Surfaces B: Biointerfaces, 2013
- PHYSICO-CHEMICAL AND PHYTOCHEMICAL EVALUATION OF CARICA PAPAYA LINN. UNRIPE FRUITSINTERNATIONAL RESEARCH JOURNAL OF PHARMACY, 2013
- Restoration of tensile strength in bark samples of Ficus benjamina due to coagulation of latex during fast self-healing of fissuresAnnals of Botany, 2011
- Preparation, characterization, in vitro drug release and biological studies of curcumin loaded dextran sulphate–chitosan nanoparticlesCarbohydrate Polymers, 2011
- Biomedical applications of chitin and chitosan based nanomaterials—A short reviewCarbohydrate Polymers, 2010
- A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticlesColloids and Surfaces B: Biointerfaces, 2010
- Latex: A Model for Understanding Mechanisms, Ecology, and Evolution of Plant Defense Against HerbivoryAnnual Review of Ecology, Evolution, and Systematics, 2009
- Gum Arabic-Coated Magnetic Nanoparticles for Potential Application in Simultaneous Magnetic Targeting and Tumor ImagingThe AAPS Journal, 2009
- Vein-Cutting Behavior: Insect Counterploy to the Latex Defense of PlantsScience, 1987
- Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysJournal of Immunological Methods, 1983