Bifunctional chiral synthons via biochemical methods. 5. Preparation of (S)-ethyl hydrogen-3-hydroxyglutarate, key intermediate to (R)-4-amino-3-hydroxybutyric acid and L-carnitine.
Authors:
- Aravamudan S. GopalanAGAravamudan S. Gopalan
- Charles J. SihCSCharles J. Sih
- 1 January 1984
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 25 (46) , 5235-5238
Abstract
No abstract availableThis publication has 13 references indexed in Scilit:
- A Study of Stereoselective Hydrolysis of Symmetrical Diesters with Pig Liver EsteraseHelvetica Chimica Acta, 1983
- Stereochemical control of yeast reductions. 1. Asymmetric synthesis of L-carnitineJournal of the American Chemical Society, 1983
- Synthesis of S- and R-4-Amino-3-hydroxybutyric Acid (GABOB) and S- and R-Carnitine from Arabinose or Ascorbic Acid.Acta Chemica Scandinavica, 1983
- Possible Carnitine Requirement of the Newborn and the Effect of Genetic Disease on the Carnitine RequirementNutrition Reviews, 1981
- Systemic Carnitine Deficiency — A Treatable Inherited Lipid-Storage Disease Presenting as Reye's SyndromeNew England Journal of Medicine, 1980
- Total synthesis of (R)-glycerol acetonide and the antiepileptic and hypotensive drug (-)-.gamma.-amino-.beta.-hydroxybutyric acid (GABOB): use of vitamin C as a chiral starting materialJournal of the American Chemical Society, 1980
- Convenient Synthesis of (RS)-4-Amino-3-hydroxybutyri AcidJournal of Pharmaceutical Sciences, 1978
- On the Absolute Configuration of l-Carnitine (Vitamin BT)Bulletin of the Chemical Society of Japan, 1962
- Requirements for Stereospecificity in Hydrolysis by α-Chymotrypsin. IV. The Hydroxyl Substituent. Absolute Configurations1Journal of the American Chemical Society, 1961
- CONTRIBUTION TO THE KNOWLEDGE OF γ-AMINOCROTONIC ACID. VINYLOGS OF α-AMINO ACIDS. IThe Journal of Organic Chemistry, 1954