Microimaging FTIR of head and neck tumors. IV
Open Access
- 12 January 2009
- journal article
- research article
- Published by Wiley in Microscopy Research and Technique
- Vol. 72 (2) , 67-75
Abstract
On continuing our studies on head and neck neoplasia, specimens from salivary gland tumors have been explored by using infrared microimaging spectroscopy to discern healthy from neoplastic tissues. Samples with Warthin tumor, epithelial displasia, marginal B‐cell lymphoma, low‐grade adenocarcinoma, and adenoid cystic carcinoma pathologies have been investigated by using conventional light sources. Changes were monitored at the molecular level, probing spectral markers such as Amide I and II, phosphate, nucleic acids, and carbohydrates vibrational modes. In all cases, supervised and unsupervised spectral analyses resulted in satisfactory agreement with histopathological findings. Microsc. Res. Tech., 2009.Keywords
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