Design at the atomic level: Generation of novel hybrid biaryloxazolidinones as promising new antibiotics
Authors:
- Ashoke BhattacharjeeABAshoke Bhattacharjee
- Shili ChenSCShili Chen
- Yi ChenYCYi Chen
- Erin DuffyEDErin Duffy
- Jay FarmerJFJay Farmer
- Joel GoldbergJGJoel Goldberg
- Roger HanselmannRHRoger Hanselmann
- Joseph A. IppolitoJIJoseph A. Ippolito
- Rongliang LouRLRongliang Lou
- Alia OrbinAOAlia Orbin
- Ayomi OyelereAOAyomi Oyelere
- 1 December 2008
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 18 (23) , 6179-6183
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- Design at the atomic level: Design of biaryloxazolidinones as potent orally active antibioticsBioorganic & Medicinal Chemistry Letters, 2008
- Structure-based drug design meets the ribosomeBiochemical Pharmacology, 2006
- Recent advances in oxazolidinone antibacterial agent researchExpert Opinion on Therapeutic Patents, 2004
- Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal SubunitJournal of Molecular Biology, 2003
- Carbon–carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteriaBioorganic & Medicinal Chemistry, 2001
- Linezolid resistance in a clinical isolate of Staphylococcus aureusThe Lancet, 2001
- Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolidThe Lancet, 2001
- LINEZOLIDInternational Journal Of Clinical Practice, 2001
- Total synthesis of the antibiotic sparsomycin, a modified uracil amino acid monoxodithioacetalThe Journal of Organic Chemistry, 1981