Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dose-dependent, phase IV clinical trial
Authors:
- Juan J JiménezJuan J Jiménez
- José L IribarrenJosé L Iribarren
- Maitane BrouardMaitane Brouard
- Domingo HernándezDomingo Hernández
- Salomé PalmeroSalomé Palmero
- Alejandro JiménezAlejandro Jiménez
- Leonardo LorenteLeonardo Lorente
- Patricia MachadoPatricia Machado
- Juan M BorregueroJuan M Borreguero
- José M RayaJosé M Raya
- Beatriz MartínBeatriz Martín
- Rosalía PérezRosalía Pérez
Open Access
- 14 October 2011
- journal article
- research article
- Published by Springer Nature in Journal of Cardiothoracic Surgery
- Vol. 6 (1) , 138
Abstract
In cardiopulmonary bypass (CPB) patients, fibrinolysis may enhance postoperative inflammatory response. We aimed to determine whether an additional postoperative dose of antifibrinolytic tranexamic acid (TA) reduced CPB-mediated inflammatory response (IR).Keywords
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