Abstract
A 20-year-old woman notes having had recurrent painful mouth ulcers for the past 10 years. She is otherwise healthy and reports no genital or anal ulcers, skin lesions, gastrointestinal or joint problems, or fevers. Physical examination reveals several ulcers, 3 mm in diameter, on her buccal mucosae. She has no lesions on the skin or on other mucosal surfaces. How should she be evaluated and treated?

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