Blood Glucose Variations and Clinical Experience with Glibenclamide in Diabetes Mellitus

Authors:
  • DOD. J. O'SUllivan
    D. J. O'SUllivan
  • WCW. F. Cashman
    W. F. Cashman

Abstract
Thirty patients were treated with glibenclamide for periods up to 16 months. The drug is a potent hypoglycaemic agent, and taken in a single daily dose controls blood glucose levels over a 24-hour period in maturity onset diabetes. A definite dose-effect relationship exists, and the drug may be used in doses of 5 to 20 mg. daily. There were no appreciable side-effects or toxic effects during the period of study.