Herbal medicines to the treatment of skin and soft tissue infections: advantages of the multi‐targets action
Authors:
- Tatiane Roquete AmparoTATatiane Roquete Amparo
- Janaína Brandão SeibertJSJanaína Brandão Seibert
- Paula Melo de Abreu VieiraPVPaula Melo de Abreu Vieira
- Luiz Fernando Medeiros TeixeiraLTLuiz Fernando Medeiros Teixeira
- Orlando David Henrique dos SantosOSOrlando David Henrique dos Santos
- Gustavo Henrique Bianco de SouzaGSGustavo Henrique Bianco de Souza
- 11 November 2019
- journal article
- review article
- Published by Wiley in Phytotherapy Research
- Vol. 34 (1) , 94-103
Abstract
The research for new treatments of skin and soft tissue infections (SSTIs) is important due to their high prevalence and number of hospitalizations. The purpose of this review is to address the pathophysiology of SSTIs to highlight the advantages of herbal medicines to their treatment, showing examples of species and compounds with multi‐targets action. SSTIs have a complex physiopathology involving the microorganism, as well as inflammation and difficult healing. Therefore, antimicrobial, anti‐inflammatory, antioxidant and healing activities are an approach possible for their treatment. Herbal medicines have a wide diversity of biological compounds, mainly phenolic compounds that may act on different targets and also have synergism between them. Therefore, a single medicine may have the four key activities that allied allow eliminating the infection, control the inflammation process and accelerating the healing process, preventing complications with chronic infections.Keywords
Funding Information
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais (APQ‐02004‐14)
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG ‐ CDS ‐ APQ‐02004‐14)
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