Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status

This publication has 37 references indexed in Scilit:

• Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet
  Carcinogenesis, 2007
• Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts
  Leukemia, 2007
• Dietary Folate Intake in Combination with MTHFR C677T Genotype and Promoter Methylation of Tumor Suppressor and DNA Repair Genes in Sporadic Colorectal Adenomas
  Cancer Epidemiology, Biomarkers & Prevention, 2007
• Low folate levels may protect against colorectal cancer
  Gut, 2006
• Folate and its preventive potential in colorectal carcinogenesis.
  Critical Reviews in Oncology/Hematology, 2005
• Epidemiological changes in colorectal cancer in Shiraz, Iran: 1980−2000
  Anz Journal of Surgery, 2004
• Hypermethylation pathways to colorectal cancer
  Gastroenterology Clinics of North America, 2002
• Intake of dietary folate vitamers and risk of colorectal carcinoma
  Cancer, 2002
• Mortality risk in men is associated with a common mutation in the methylenetetrahydrofolate reductase gene (MTHFR)
  European Journal of Human Genetics, 1999
• A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
  Nature Genetics, 1995