Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways
Authors:
- Xiaozhong YuXYXiaozhong Yu
- Joshua F. RobinsonJRJoshua F. Robinson
- Jaspreet S. SidhuJSJaspreet S. Sidhu
- Elaine M. FaustmanEFElaine M. Faustman
- 1 December 2008
- journal article
- Published by Elsevier in Toxicology and Applied Pharmacology
- Vol. 233 (3) , 389-403
Abstract
No abstract availableKeywords
This publication has 56 references indexed in Scilit:
- A System-Based Comparison of Gene Expression Reveals Alterations in Oxidative Stress, Disruption of Ubiquitin-Proteasome System and Altered Cell Cycle Regulation after Exposure to Cadmium and Methylmercury in Mouse Embryonic FibroblastToxicological Sciences, 2010
- Arsenic trioxideExpert Opinion on Pharmacotherapy, 2008
- Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 statusGenome Biology, 2008
- A System-Based Approach to Interpret Dose- and Time-Dependent Microarray Data: Quantitative Integration of Gene Ontology Analysis for Risk AssessmentToxicological Sciences, 2006
- Cell Cycle Inhibition by Sodium Arsenite in Primary Embryonic Rat Midbrain Neuroepithelial CellsToxicological Sciences, 2005
- A P53 target gene, PIG11, contributes to chemosensitivity of cells to arsenic trioxideFEBS Letters, 2004
- p53-regulated Transcriptional Program Associated with Genotoxic Stress-induced ApoptosisJournal of Biological Chemistry, 2004
- Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosisMolecular Reproduction and Development, 2003
- GenMAPP, a new tool for viewing and analyzing microarray data on biological pathwaysNature Genetics, 2002
- Significance analysis of microarrays applied to the ionizing radiation responseProceedings of the National Academy of Sciences, 2001