Highly efficient base editing at PCSK9 and normal human embryo development
- 9 September 2026
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 658 (8138) , 1289-1300
Abstract
No abstract availableKeywords
This publication has 87 references indexed in Scilit:
- Preparation of high-purity RNPs of CRISPR-based DNA base editors2025
- Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNACell, 2024
- Replication stress impairs chromosome segregation and preimplantation development in human embryosCell, 2022
- Heritable human genome editing: Research progress, ethical considerations, and hurdles to clinical practiceCell, 2021
- Allele-Specific Chromosome Removal after Cas9 Cleavage in Human EmbryosCell, 2020
- Validation of concurrent preimplantation genetic testing for polygenic and monogenic disorders, structural rearrangements, and whole and segmental chromosome aneuploidy with a single universal platformEuropean Journal of Medical Genetics, 2019
- Correction of β-thalassemia mutant by base editor in human embryosProtein & Cell, 2017
- Highly efficient base editing in human tripronuclear zygotesProtein & Cell, 2017
- Highly efficient and precise base editing in discarded human tripronuclear embryosProtein & Cell, 2017
- First Unaffected Pregnancy Using Preimplantation Genetic Diagnosis for Sickle Cell AnemiaJAMA, 1999