Cloning and Nucleotide Sequence of senN, a Novel 'Bacillus natto' (B. subtilis) Gene That Regulates Expression of Extracellular Protein Genes

Authors:
  • LWL.-F. Wang
    L.-F. Wang
  • RDR. H. Doi
    R. H. Doi
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Abstract
A new ''Bacillus natto'' gene, senN, that regulates the expression of several extracellular proteins in B. subtilis has been cloned and sequenced. senN codes for a small, highly basic protein with an amino acid sequence different from the products coded by the regulatory genes sacQ, sacV, prtR and hpr. SenN stimulates gene expression at the transcriptional level. A putative homologous locus has been detected in the B. subtilis chromosome by Southern blotting.