Haptoglobin-hemoglobin receptor independent killing of African trypanosomes by human serum and trypanosome lytic factors
Open Access
- 1 January 2012
- journal article
- Published by Taylor & Francis in Virulence
- Vol. 3 (1) , 72-76
Abstract
The haptoglobin-hemoglobin receptor (HpHbR) of African trypanosomes plays a critical role in human innate immunity against these parasites. Localized to the flagellar pocket of the veterinary patho...Keywords
This publication has 26 references indexed in Scilit:
- Endosomal Localization of the Serum Resistance-Associated Protein in African Trypanosomes Confers Human InfectivityEukaryotic Cell, 2011
- Mechanism of Trypanosoma brucei gambiense (group 1) resistance to human trypanosome lytic factorProceedings of the National Academy of Sciences, 2010
- The trypanolytic factor of human serum: many ways to enter the parasite, a single way to killMolecular Microbiology, 2010
- Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse modelJournal of Experimental Medicine, 2008
- Hemoglobin Is a Co-Factor of Human Trypanosome Lytic FactorPLOS Pathogens, 2007
- Switching trypanosome coats: what's in the wardrobe?Trends in Genetics, 2006
- In Vitro Generation of Human High-Density-Lipoprotein-Resistant Trypanosoma brucei bruceiEukaryotic Cell, 2006
- Trypanosome lytic factor, a subclass of high-density lipoprotein, forms cation-selective pores in membranesMolecular and Biochemical Parasitology, 2005
- Apolipoprotein L-I is the trypanosome lytic factor of human serumNature, 2003
- Evidence for a Trypanosoma brucei Lipoprotein Scavenger ReceptorJournal of Biological Chemistry, 2003