Intramolecular Cycloaddition of Azomethine Ylides in the Preparation of Pyrrolidino[2‘,3‘:3,4]pyrrolidino[1,2- a]benzimidazoles

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Abstract
The parent pyrrolidino[2‘,3‘:3,4]pyrrolidino[1,2-a]benzimidazole heterocycle as well as a series of novel analogues have been synthesized utilizing a microwave-assisted intramolecular cycloaddition of azomethine ylides as the key transformation. A variety of diversity groups were added to explore the scope of this reaction and to provide a number of new compounds for biological screening.

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