Prothrombin conversion accelerates with increasing age in women but not in men: findings from the Moli-sani Cohort Study
Authors:
- Amalia De CurtisACAmalia De Curtis
- Romy de Laat-KremersRLRomy de Laat-Kremers
- Simona CostanzoSCSimona Costanzo
- Augusto Di CastelnuovoACAugusto Di Castelnuovo
- Marisa NinivaggiMNMarisa Ninivaggi
- Chiara CerlettiCCChiara Cerletti
- Giovanni de GaetanoGGGiovanni de Gaetano
- Maria Benedetta DonatiMDMaria Benedetta Donati
- Licia IacovielloLILicia Iacoviello
- Bas de LaatBLBas de Laat
- Marialaura BonaccioMBMarialaura Bonaccio
- Americo BonanniABAmerico Bonanni
Open Access
- 30 December 2025
- journal article
- Published by Elsevier in Research and Practice in Thrombosis and Haemostasis
- Vol. 10 (1)
Abstract
No abstract availableKeywords
Funding Information
- Seventh Framework Programme (HEALTH-F2-2011-278913)
- Ministero dell’Istruzione, dell’Università e della Ricerca (1588)
- Ministero della Salute (PE0000015)
- Ministero della Salute (2025-2027)
- European Commission
- Pfizer Foundation
- Ministero dell'Università e della Ricerca
This publication has 63 references indexed in Scilit:
- Effects of hormonal therapy on thrombin generation testing in transgender individualsJournal of Thrombosis and Haemostasis, 2025
- The thrombin generation potential increases after feminizing gender-affirming hormone treatment, decreases after masculinizing gender-affirming hormone treatment, and is determined by the hormone treatment regimenJournal of Thrombosis and Haemostasis, 2025
- Low thrombin inactivation capacity is associated with an increased risk of recurrent ischemic events after ischemic stroke at a young ageJournal of Thrombosis and Haemostasis, 2024
- Fibrinogen, Coagulation, and Ageing2023
- ST Genesia reference values of 117 healthy donors measured with STG‐BleedScreen, STG‐DrugScreen and STG‐ThromboScreen reagentsResearch and Practice in Thrombosis and Haemostasis, 2020
- Standardization and evaluation of the performance of the thrombin generation test under hypo- and hypercoagulability conditionsHematology, Transfusion and Cell Therapy, 2019
- Correlates of plasma and platelet tissue factor pathway inhibitor, factor V, and Protein SResearch and Practice in Thrombosis and Haemostasis, 2018
- Prothrombotic State in Asthma Is Related to Increased Levels of Inflammatory Cytokines, IL-6 and TNFα, in Peripheral BloodInflammation, 2017
- Thrombin generation: What have we learned?Blood Reviews, 2012
- Sex and gender issues and venous thromboembolismClinics in Chest Medicine, 2004