The role of inflammation in ICU-acquired weakness
Open Access
- 3 August 2010
- journal article
- editorial
- Published by Springer Nature in Critical Care
- Vol. 14 (4) , 1-2
Abstract
A pilot observational study by Weber-Carstens and colleagues contributes to a mechanistic explanation of the puzzling and complex phenomena of ICU-acquired weakness (ICU-AW). The authors suggest systemic, inflammatory-mediated pathology is the most significant risk factor for ICU-AW. While this finding is somewhat equivocal, it provides important direction for future investigations and illustrates the challenges of interpreting significance in small observational studies.Keywords
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