Fast and accurate protein structure search with Foldseek
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Abstract
Highly accurate structure prediction methods are generating an avalanche of publicly available protein structures. Searching through these structures is becoming the main bottleneck in their analysis. Foldseek enables fast and sensitive comparisons of large structure sets. It reaches sensitivities similar to state-of-the-art structural aligners while being at least 20,000 times faster. Foldseek is free open-source software available at foldseek.com and as a webserver at search.foldseek.com. Contact soeding{at}mpinat.mpg.de , martin.steinegger{at}snu.ac.krKeywords
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- Published version: Nature Biotechnology, 42 (2), 243.
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