Clostridium difficile-Associated Diarrhea After Norfloxacin

Authors:
  • MLMichael W. Lievens
    Michael W. Lievens
  • RCRobert M. Craig
    Robert M. Craig
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Abstract
Although theoretically the spectrum of antimicrobial quinolone antibiotics are at low risk of producing Clostridium difficile overgrowth and diarrhea, a patient developed this clinical problem while receiving norfloxacin. We review the antimicrobial activity of the quinolone antibiotics, with respect to their predisposition for producing C. difficile-induced diarrhea.