Delayed Enhancement of Fibrotic Areas in Hepatic Masses

Authors:
  • OMOsamu Matsui
    Osamu Matsui
  • MKMasumi Kadoya
    Masumi Kadoya
  • TGToshifumi Gabata
    Toshifumi Gabata
  • KAKazunori Arai
    Kazunori Arai
  • TTTsutomu Takashima
    Tsutomu Takashima

Abstract
We report a histological analysis of the areas of high density in the postequilibrium and delayed phase CT in 43 focal hepatic lesions. The cases consisted of 16 cholangiocellular carcinomas, 9 hepatocellular carcinomas (including a sclerosing type of hepatocellular carcinoma and a combined hepatocellular-cholangiocellular carcinoma), 13 metastases, 2 granulomas, an inflammatory pseudotumor, a malignant lymphoma, and an epithelioid hemangioendothelioma. Computed tomography was performed after hepatic angiography using 40-50 g iodine and arteriographic CT using 35 g iodine. The areas of delayed enhancement corresponded histologically to fibrotic tissues, from inflammatory change to extensive fibrosis.