Clinical Predictive Model of Multidrug Resistance in Neutropenic Cancer Patients with Bloodstream Infection Due to Pseudomonas aeruginosa
- 24 March 2020
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 64 (4)
Abstract
We aimed to assess the rate and predictive factors of bloodstream infection (BSI) due to multidrug-resistant (MDR) Pseudomonas aeruginosa in neutropenic cancer patients. We performed a multicenter, retrospective cohort study including oncohematological neutropenic patients with BSI due to P. aeruginosa conducted across 34 centers in 12 countries from January 2006 to May 2018. A mixed logistic regression model was used to estimate a model to predict the multidrug resistance of the causative pathogens.Keywords
Funding Information
- Spanish Network for Research in Infectious Diseases (REIPI (REIPI RD16/0016/0001)
This publication has 34 references indexed in Scilit:
- Contribution of specific pathogens to bloodstream infection mortality in neutropenic patients with hematologic malignancies: Results from a multicentric surveillance cohort studyTransplant Infectious Disease, 2019
- Bacteremia due to carbapenem-resistant Enterobacteriaceae in neutropenic patients with hematologic malignanciesJournal of Infection, 2016
- Bloodstream infections in neutropenic cancer patients: A practical updateVirulence, 2016
- Aetiology and resistance in bacteraemias among adult and paediatric haematology and cancer patientsJournal of Infection, 2014
- Changing aetiology, clinical features, antimicrobial resistance, and outcomes of bloodstream infection in neutropenic cancer patientsClinical Microbiology and Infection, 2013
- Quantitative and qualitative differences in use and trends of hematopoietic stem cell transplantation: a Global Observational StudyHaematologica, 2013
- Multidrug resistant Pseudomonas aeruginosa infection in children undergoing chemotherapy and hematopoietic stem cell transplantationHaematologica, 2010
- Incidence and clinical impact of extended-spectrum-β-lactamase (ESBL) production and fluoroquinolone resistance in bloodstream infections caused by Escherichia coli in patients with hematological malignanciesJournal of Infection, 2009
- Infections in Patients with Febrile Neutropenia: Epidemiology, Microbiology, and Risk StratificationClinical Infectious Diseases, 2005
- Analysis of 553 episodes of monomicrobial bacteraemia in cancer patients: any association between risk factors and outcome to particular pathogen?Supportive Care in Cancer, 1997