Structure–activity relationships of 1,5-dihydro-2 H -benzo[ b ][1,4]diazepine-2,4(3 H )-diones as inhibitors of Trypanosoma cruzi

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Abstract
Two related series of benzodiazepinediones were synthesised, profiled for their suitability as novel treatments for Chagas disease, and progressed to a T. cruzi washout assay.
Funding Information
  • Wellcome Trust (203134/Z/16/Z)
  • Wellcome Trust (224024/Z/21/Z)

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