Aggregation of human platelets by commercial preparations of bovine and porcine antihaemophilic globulin
Authors:
- R. D. BarrRBR. D. Barr
Open Access
- 1 March 1972
- journal article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 25 (3) , 210-217
Abstract
Infusion of commercial preparations of porcine and bovine antihaemophilic globulin into three haemophilic patients produced transient thrombocytopenia. This platelet-aggregating activity has been shown to be present in a wide range of animal plasmas and is related to the fibrinogen fraction. The mechanism of platelet aggregation by animal fibrinogen is discussed and some inhibitors of the reaction are described.Keywords
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