Hypoxia-induced nitric oxide release by luminal cells stimulates proliferation and uPA secretion of myoepithelial cells in a bicellular murine mammary tumor
- 17 February 2015
- journal article
- research article
- Published by Springer Nature in Journal of Cancer Research and Clinical Oncology
- Vol. 141 (10) , 1727-1738
Abstract
LM38 murine mammary adenocarcinoma model is formed by LM38-LP (myoepithelial and luminal), LM38-HP (luminal) and LM38-D2 (myoepithelial) cell lines. In a previous work, we had shown that LM38-HP and LM38-D2 cell lines are less malignant than the bicellular LM38-LP cell line.Keywords
This publication has 56 references indexed in Scilit:
- Myoepithelial Carcinoma of the BreastJournal of Clinical and Diagnostic Research, 2013
- Comprehensive molecular portraits of human breast tumoursNature, 2012
- Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic SuccessCancer Cell, 2012
- Hallmarks of Cancer: The Next GenerationCell, 2011
- Increased NOS2 predicts poor survival in estrogen receptor–negative breast cancer patientsJournal of Clinical Investigation, 2010
- Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasionBritish Journal of Cancer, 2009
- Tumor-associated macrophages (TAM) as major players of the cancer-related inflammationJournal of Leukocyte Biology, 2009
- Molecular mechanisms for discrete nitric oxide levels in cancerNitric Oxide, 2008
- The chemical biology of nitric oxide: Implications in cellular signalingFree Radical Biology and Medicine, 2008
- The role of early expression of inducible nitric oxide synthase in human breast cancerEuropean Journal of Cancer, 2005