Change of the Higher Order Structure in a Giant DNA Induced by 4′, 6-Diamidino-2-phenylindole as a Minor Groove Binder and Ethidium Bromide as an Intercalator
Authors:
- 1 July 1994
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 13 (6-7) , 1415-1423
Abstract
From a quantitative study of the contour length and the persistent length of DNA molecules with fluorescence microscopy, it is shown that 4′, 6-diamidino-2-phenylindole (DAPI) and ethidium bromide (EB) change the higher order structure of DNA in a different manner.Keywords
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