Polymeric de-blocking agents for the fluoren-9-ylmethoxycarbonyl (FMOC) amino-protecting group

Authors:
  • LCLouis A. Carpino
    Louis A. Carpino
  • JWJames R. Williams
    James R. Williams
  • AŁAndrzej Łopusiński
    Andrzej Łopusiński

Abstract
The fluoren-9-ylmethoxycarbonyl (FMOC) amino-protecting group can be de-blocked at room temperature by means of an insoluble polymeric reagent incorporating cyclic secondary amino-functions.