The use of phosphotriesterase in the synthesis of enantiomerically pure ProTide prodrugs

This publication has 83 references indexed in Scilit:

• Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
  Cell, 2020
• Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids
  Protein & Cell, 2020
• A long acting nanoformulated lamivudine ProTide
  Biomaterials, 2019
• The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors
  Bioorganic & Medicinal Chemistry Letters, 2017
• Improving nucleoside analogs via lipid conjugation: Is fatter any better?
  Critical Reviews in Oncology/Hematology, 2016
• DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells
  Biochemical and Biophysical Research Communications, 2012
• Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148
  Bioorganic & Medicinal Chemistry, 2010
• Aryloxy Phosphoramidate Triesters: a Technology for Delivering Monophosphorylated Nucleosides and Sugars into Cells
  ChemMedChem, 2009
• A practical synthesis of (2R)-3,5-di-O-benzoyl-2-fluoro-2-C-methyl-d-ribono-γ-lactone
  Tetrahedron: Asymmetry, 2009
• Stereospecificity in the enzymatic hydrolysis of cyclosarin (GF)
  Enzyme and Microbial Technology, 2005