When non-coding is not enough
Open Access
- 5 February 2020
- journal article
- editorial
- Published by Rockefeller University Press in Journal of Experimental Medicine
- Vol. 217 (3)
Abstract
A new concept is emerging in the non-coding RNA (ncRNA) field: an increasing number of ncRNAs in fact codify for short peptides that have biological activities. In this issue of JEM, Wang et al. (https://doi.org/10.1084/jem.20190950) report the identification of a long ncRNA (lncRNA)–encoded 60–amino acid polypeptide that they name ASRPS, as well as its ability to inhibit angiogenesis in the deadly triple-negative breast cancer (TNBC).Keywords
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