Are eosinophil leucocytes involved in the oestrogenic response of the postnatal rat epididymis?

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Abstract
The effects of estrogens and androgens, alone or in combination, on several epididymal parameters have been studied in 15-day-old rats after neonatal treatment. Estrogens induced several responses, such as increased growth of the fibromuscular stroma and eosinophil leukocyte accumulation, whereas the proliferative activity of the epithelium was decreased significantly. Otherwise, the density of intra-epithelial leukocytes was not modified. Different estrogen-induced responses, such as the increase in volume of the fibromuscular stroma and eosinophil leukocyte accumulation were inhibited by treatment with testosterone, whereas dihydrotestosterone had no appreciable effect. This study raises the possibiliy that eosinophils are mediators are some of the estrogenic responses in the early postnatal rat epididymis.

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