Unlocking the therapeutic potential of ATR inhibitors: Advances, challenges, and opportunities in cancer therapy
Open Access
- 17 July 2025
- journal article
- Published by Wiley in Clinical and Translational Medicine
- Vol. 15 (7) , e70397
Abstract
No abstract availableThis publication has 9 references indexed in Scilit:
- Targeting ATR in patients with cancerNature Reviews Clinical Oncology, 2024
- Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial resultsNature Medicine, 2023
- First-in-Human Trial of the Oral Ataxia Telangiectasia and RAD3-Related (ATR) Inhibitor BAY 1895344 in Patients with Advanced Solid TumorsCancer Discovery, 2020
- ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migrationNature Communications, 2020
- ATM Loss Confers Greater Sensitivity to ATR Inhibition Than PARP Inhibition in Prostate CancerCancer Research, 2020
- A decade of clinical development of PARP inhibitors in perspectiveAnnals of Oncology, 2019
- State-of-the-art strategies for targeting the DNA damage response in cancerNature Reviews Clinical Oncology, 2018
- Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical OutcomesCell Stem Cell, 2017
- ATR: an essential regulator of genome integrityNature Reviews Molecular Cell Biology, 2008